Amicus Therapeutics and the Treatment of Rare Diseases

Amicus Therapeutics is a biotechnology company that focuses on researching treatment for rare and orphan diseases. Although the company is based in Cranbury, New Jersey, they operate a second research site in San Diego, California. Amicus was founded in 2002 but didn’t go public until 2007. The company is fairly small, with around five hundred employees. Amicus is primarily research based and has to have other companies take care of manufacturing. Although the company offers no products as of 2017, a few potential products are in the final stages of being approved for commercial use.

Fabry Disease is one illness that Amicus Therapeutics is currently researching. The company has developed two potential products to help treat it: Galafold/Migalastat Monotherapy and novel ERTs (Enzyme Replacement Therapy). Galafold is an orally administered monotherapy that has full approval in Europe and is ready to be released to the public. Migalastat Monotherapy and Galafold are one in the same, with Galafold being the brand name. While the product is ready for use in Europe, it is still in the approval stages in the Americas and the rest of the world. Amicus’ ERTs for Fabry Disease are in preclinical stages of research.
In addition to Fabry Disease, Amicus Therapeutics studies two other illnesses specifically, Pompe Disease and Epidermolysis Bullosa. Their product for Pompe Disease, a novel ERT named ATB200 and AT2221 are in the middle of the final phase of testing. This treatment will require a chaperone as well. Amicus’ medication for Epidermolysis Bullosa is named SD-101. It is a topical medication. Currently, SD-101 is in the third and final phase of testing.
While Amicus Therapeutics focuses on a few diseases specifically, they also conduct research on other rare diseases and plan treatments for patients with these illnesses. Most of their medications for these various diseases are novel ERTs and most of them are in the primary research phase of development.
Dedicated to research and creating treatments for those with rare illnesses, Amicus Therapeutics is a company to keep an eye on. Several products are nearing their final stages and are one step closer to helping others survive.
More here: Crunchbase

Litigation Assistance With Karl Heideck

Litigation Assistance With Karl Heideck

Any time that you are looking to get everything you need in terms of your litigation, you’ll want to touch base with a company that can help you out with this. Karl Heideck is a great lawyer who can serve you with this. Before you reach out to Heideck for service, take the time to research litigation, the type of legal aid he provides and what you need to know about hiring the right lawyer who can assist you.

What is litigation and what do litigators do?

Litigation refers to the area of law in which cases are tried or settle for a number of matters. This applies both to civil litigation and criminal litigation. So whether you are filing a lawsuit for any reason or defending yourself from charges, it is incredibly important to reach out to a professional attorney that can serve you.

What are some areas of expertise that Karl Heideck practices?

Karl Heidecke specializes in a number of legal matters. First and foremost, he has expertise in litigation. He specializes in court cases involving people in the greater Philadelphia area and the surrounding area. In addition to litigation, Karl Heideck specializes to include compliance and risk management. Compliance revolves around making sure that another party is following a set of agreed-upon principles. This could refer to anything from entering a contract to negotiating and sticking to a collective bargaining agreement. Risk management allows a party to be sure that they are not falling prey to some legal liabilities which can be troublesome and expensive in the long run.

You will be in good hands by reaching out to Karl Heideck, because he has the experience and educational background to serve you. For example, he received his law degree with honors from Tempe University. In addition to litigation and compliance, Karl Heideck specializes in other areas, such as product liability and legal writing.

Take advantage of these tips so that you can make the most out of your legal needs.

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Wild Ark Wildlife Travel

My wife and I love SCUBA diving. When we lived in China for 13 months as foreign teachers we were able to travel to exotic destinations all around South-East Asia. One of our favorites was Mabul Island in Malaysian Borneo.


Surrounded by pristine water and friendly faces it was no wonder that this was one of the best and most eco-friendly places to dive in the world. Hawksbill and Green Sea turtle conservation efforts are steadily on the rise on this small island paradise. Learn more:


The local Malaysians and some Filipinos living on this island once ate turtle eggs regularly as they are a prevalent source of food and can be used for a variety of dishes. But luckily local dive shops have pooled together to give money in exchange for every turtle egg turned over by the local Malaysians. In turn, this keeps the local turtle population safe from interference. Learn more:


Conservation organization Wild Ark also seeks to protect turtles around the world in places like Watuma Bay, Kenya where their Local Ocean Conservation (LOC) invites locals to protect and enjoy their own sea turtle wildlife. With Wild Ark you can stay in unique accommodations and explore the wildlife surrounding this beautiful destination in Coastal Africa. Learn more:


Wild Ark’s purpose is to conserve various green areas around the world. In doing so they also spread a message of conservation and the importance of nature and it’s effect on our everyday life. By partnering with them, you can aid in their mission of making our planet a safer place for wildlife.


Founders Mark and Sophie Hutchinson hope that their passion for wildlife conservation will pass on to future generations. Along with their many Wild Ark ambassadors, Mark and Sophie have compiled stories, news and even tours where you can explore parts of the world where the vision for wildlife conservation is taking place. Please join us.


Our Story


Uncovering Jail Secrets Using the Securus Technologies System

Working in a very crowded prison is a very dangerous job for me and all my fellow corrections officers. In recent weeks we noticed that inmates were getting their hands on more contraband than they had in years. We decided to step p our efforts in a number of areas to try and curb the problem.


The visitor center is the most vulnerable because here is where the inmates get to interact with people on the outside, and if persuaded, will bring things into the prison for those inmates. My team has to check each visitor with a physical search, run them through a metal detector, and even an x-ray machine. These inmates have come up with very creative ways for those visitors to get them what they need.


Even with the threat of the visitors spending time in jail for violating these rules, the issue seemed to be getting worse. It was around this time that we had Securus Technologies in the prison and setting up our brand new inmate call monitor system. The LBS software was going to do the job of several officers, allowing us to listen in on every minute of every call more intently.


Not a day after we started listening to the calls did we discover more inmates talking about using drugs in their cells or scoring more drugs from other inmates. It was one call in particular that would normally have slipped by that opened a can of worms that broke the case wide open.


One inmate was giving his visitor detailed instructions how to enter the jail, to the point it was very suspicious. The inmate was told to see a certain corrections officer, one who later was revealed to be corrupt and making more in letting people pass than he did on the job.

Whitney Wolfe And Her Leadership At Bumble

Whitney Wolfe is the CEO of Bumble, and she has created an atmosphere around the company that the public enjoys. This article explains how the company is offering the best services to women who wish to date, and they are growing every day in new and interesting ways.

Whitney Wolfe is one of the best tech executives in the world, and she is showing why she has been lauded for her work many times over.

#1: Bumble Is Growing

Bumble is growing with the Bumble BFF app that will help women make friends in the same way they have dated. The person who has downloaded the app may use it to make friends, and they will find that there are a number of different people who may have the same interests as them.

#2: The Dating App

The dating app gives women quite a lot of control because they decide which men they want to talk to. They will notice how simple it is to keep away any man who would harass them, and they will give men a chance to talk only if they have been vetted. Whitney Wolfe created this app to ensure that women would feel safe, and she has grown the app with the safety marketing angle.

#3: Her Leadership

Whitney Wolfe has led the company for many years, and she is helping it grow to ensure that the women who want to date in a better way will feel the freedom that comes with this app. The app is easy for women to put on their phones, and the app is easier for women to use when they want to meet men in a better environment.

The Bumble has become a worldwide name that everyone knows or wants to try. The app has grown from its origins to help all women Date safely, and they are coming out with an app that will help women make friends. The woman who wishes to have a much better time making friends will notice how simple it is to start this new app to find new friends in their area.

Follow Whitney Wolfe on Instagram.

Sheldon Lavin: The Brilliant CEO Of OSI Group

Sheldon Lavin is one of the most crucial people in OSI Group and has played a major part in the company’s success in recent times. Sheldon Lavin leads the company from his position of CEO and has proven to be a perfect fit for the company. Sheldon Lavin, however, did not start out in the field of meat production, but rather in the field of finance.

Infact, before Sheldon Lavin worked at OSI Group, the company was one of his clients. In the 1970s, when the company was undergoing a significant change with their production, Sheldon Lavin was responsible for making sure that the company’s finances were in order and that everything was fine with the deals that they had with some large clients. He worked extremely closely with the leadership of OSI at the time and then decided to switch over to the company and work full time.

Sheldon Lavin has been extremely beneficial to OSI group and has set in motion numerous changes which have improved the working of the company. He was responsible for the company’s recent upgrade in technology which they use for their processing units. One of the reasons why OSI group has managed to stay atop the competition is because they have constantly adapted to everything that is new in the meat processing industry – right from the machines they use, to their packaging.

As CEO, Sheldon Lavin is one of the most vital parts of the company and works alongside the leaders to ensure that the company gives their clients the best product possible. He was also instrumental in taking OSI Group to international waters. Currently, OSI Group has its production units in countries like China. McDonald’s’ there as well are being supplied with meat by OSI Group, making them a truly globalized company.

What makes Sheldon Lavin such a Great CEO is the fact that he is dedicated to the success of OSI Group. A food lover himself, he tries his best to ensure that OSI Group is always putting out only the highest grade of products for their clients and their consumers.

Learn more about Sheldon Lavin on

Eva Moskowitz And Her Leadership Of Success Academy

Eva Moskowitz is the CEO of Success Academy, and she has had a distinguished career in education that has brought her to this place. She is leading one of the finest educational companies in America, and she is putting together schools that will serve children well no matter their educational needs. This article explains how Eva has done the work that is required to grow this brand.


#1: Eva Moskowitz And Success Academy


Eva Moskowitz is known today for being the CEO of Success Academy, and she has spent decades in education working on many levels. She knows how to lead schools that will bring greater success to students, and she uses his public sector and private sector skill set to the table.


#2: What Does Success Academy Do?


Eva has set up Success Academy to offer personal instruction to the students who count on the school every day. They have opened many schools across America to serve kids who need an alternative education, and Eva often promotes the alternative education that these students needs. She knows that a child who is given a better education today at Success Academy will move on to greater things in the future.


#3: How Does Eva Advocate For Her Students?


Eva Moskowitz is a name that is known across the education industry for advocating on behalf of all students who need a better education. The students who come to her schools are there because they need to be taught in a new way, and Eva leaves the Success Academy open to as many new educational techniques as possible. She would rather help students learn in a new way than force them to learn in a manner that does not work for them.


The career of Eva Moskowitz is one that has made a difference in the lives of thousands of children. The Success Academy is touching lives every day as children learn more than they could have ever imagined in a building that suits them. These children may have the dream of college realized, and Eva will continue to grow this brand to help the alternative student.

An Academy for My Hero


There have been many popular entries in sword anime. Perhaps the most recent to gain recognition is My Hero Academia (Boku no Hero Academia), which aired in the summer of 2016. With the second season currently airing in the spring, attention has been reignited toward this superhero themed anime.


The show’s main protagonist Izuku Midoriya has risen to the top of popular shounen character rankings for his realistic portrayal. In the first season, he struggles with being unable to have any superpowers in a world where nearly everyone has one. His one goal is to become a hero like his idol All Might. Despite his years of analyzing the actions of heroes, he remains the joke of his peers. Through a series of fortunate events, this changes when he encounters All Might who sees potential in Izuku after noting his bravery. After rigorous training, Izuku gains the power of All Might much to his elation.


It is not all sunshine and games for Izuku just yet in this ninja anime. He must now not only deal with the curriculum of the best hero academy, but also learn to control his newfound power. As he does not have the years of experience of handling a superpower, Izuku must rely on his knowledge and wit to overcome his obstacles. It is here that the young superhero becomes relatable to the viewer. Izuku demonstrates time and time again that the real power to excel and save others lies deep inside beyond any superficial power.

Five Things to Familiarize Concerning the Central Texas Regional Mobility Authority

Texas Regional Mobility Authority spearheads in constructing of transportation systems within Williamson and Travis counties. And following are some of the features and functions of Texas Regional Mobility Authority:

  • It’s a private government agency:

The CTRMA was set up in 2002, after section of state law in year 2001. entails no taxing power yet has judgment control. To fund toll road development, extension of traffic lanes on the present roads and also deals with other projects that are meant to enhance transportation. It raises 70% of its income from private firms through trading of investment bonds on stock market.

  • The governing board has more men, and development and business interests:

CTRMA’s board incorporates seven individuals, whereby three are selected by the Travis County Commissioners Court while three are chosen by the Williamson County Commissioners Court. The leader is on the other hand selected by the governor. The board entails one African-American woman while the other six individuals are white men.

  • Provides free travel apps and roadside help:

It is the responsibility of the authority to run Highway Emergency Response Operator (HERO) for stranded drivers along Interstate 35 and U.S. 183 which assist the traffic to move. In year 2015, HERO helped 14,480 stranded drivers by removing debris from highways and giving other safety guidelines to motorists.

  • The Executive Director is paid more than the Transportation Chief Texas Department:

The CTRMA overseeing board affirmed a 2016 remuneration bundle of $366,112 for organization boss, Mike Heiligenstein. That incorporated a base pay of $274,912, conceded remuneration of $45,000, yearly life protection premiums of $3,000 including a month to month auto allowance of $850.

  • It’s the one accountable for the MoPac Enhancement project:

The traffic nightmares are claimed to continue affecting some parts of North MoPac Boulevard. The venture, which entails a toll lane along the median on each side of the expressway from West Cesar Chavez Street all through to Parmer Lane, was completed later.

Mike Heiligenstein is the Central Texas Regional Mobility Authority Executive Director in Austin, Texas. The private government firm was established in year 2002 to create a modern and regional transportation system in Central Texas.

The future and present projects of the Mobility Authority are major factors within a carefully organized and multi-modal transportation framework intended to meet the assorted versatility needs of the quickly developing area. According to Biz Journals, since its inception, Mike Heilingenstein engaged with the Mobility Authority and has managed the improvement of their first venture, 183A within Williamson County.

Learn more about Mike Heilingenstein:

Vijay Eswaran of QI Group

Vijay Eswaran is an accomplished entrepreneur, a global motivational speaker, an author, and a philanthropist. He started his early childhood life in Malaysia where his parents lived and worked. Graduating with a socio-economic degree from the London School of Economics, he had odd jobs experience as a construction worker in Belgium, plucked grapes in France, and a cab driver in London.

These odd jobs did not prevent him from obtaining his accounting certification from the Chartered Institute of Management Accountants (CIMA) in the UK and subsequently his Master of Business Administration (MBA) degree from the Southern Illinois University in 1986. Read more: Dato Vijay Eswaran: From taxi driver to worth over $500 million dollars

Vijay Eswaran is the founder and Executive Chairman of QI Group of Companies with various business sectors including wholesale distribution, retailing, hospitality services, education and financial services.

In an interview with ENTREPRENEUR MAGAZINE, Vijay recounted his challenges as an entrepreneur lasting for long several years. “To me, success is as much interwoven with challenges, just as light is to shadow”, he told his interviewer. Vijay describes an entrepreneur as one who is inquisitive, intense, and intuitive. Learn more about Vijay Eswaran:

Vijay Eswaran is revered for his motivational speeches and lectures that touched the lives of individuals around the world. He gave speeches in major universities, business and leadership platforms and spiritual pulpits. He is an author having written 6 books to his credit and regularly writes informative articles for newspapers in Malaysia and Sri Lanka.

A well-known philanthropist, Vijay Eswaran founded RYTHM Foundation (RF), a division of QI Group to promote the group corporate social responsibility plans around the world. He also established Vijayaratnam Foundation in honor of his father in Malaysia.

His foundations work with local NGOs and other charitable organizations on projects in child and youth development, women forum and special education for disabled persons.

According to QBuzz, Vijay Eswaran was adjudged one of Forbes Asia’s Heroes of Philanthropy in 2011. He received the lifetime award in Regional Philanthropy for leading an independent think tank Asia Strategic Leadership Institute in Malaysia. He was also conferred with International Leader in Global Business Strategies award by the Global Organization for People of Indian Origin.